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OMEGA-AGATOXIN IVA
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DeCS
Descriptor
English
:
omega-Agatoxin IVA
Descriptor
Spanish
:
omega-Agatoxina IVA
Descriptor
Portuguese
:
omega-Agatoxina IVA
Synonyms
English
:
omega-Aga-IVA
Tree Number:
D12.644.400.562
D12.776.092.249.500
D20.888.065.870.324.500
D23.946.833.065.870.324.500
Definition
English
:
A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits
CALCIUM CHANNELS
, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits
CALCIUM CHANNELS
, Q-TYPE.
Pharmacological Action:
Calcium Channel Blockers
Neurotoxins
History Note
English
:
2000; use OMEGA-AGATOXIN IVA (NM) 1992-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
EN
enzymology
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
SE
secretion
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
34517
Unique Identifier:
D020867
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS